Mehrdad Arjomandi, MD 1,3,4, Thaddeus Haight, MA 5, Rita Redberg, MD 1,3, and Warren M Gold, MD 1,2,3
1 UCSF FAMRI Center of Excellence, University of California, San Francisco
2 Cardiovascular Research Institute, University of California, San Francisco
3 Department of Medicine, University of California, San Francisco
4 San Francisco Veterans Affairs Medical Center, University of California Berkeley, California
5 School of Public Health, University of California Berkeley, California
Objective: To determine whether the flight attendants who were exposed to secondhand tobacco smoke (SHS) in the aircraft cabin have abnormal pulmonary function.
Methods: We administered questionnaires and performed pulmonary function testing in 61 neversmoking female flight attendants who worked in active air crews before the smoking ban on commercial aircraft (pre-ban).
Results: While the pre-ban flight attendants had normal FVC, FEV1, and FEV1/FVC ratio, they had significantly decreased flow at mid- and low-lung volumes, curvilinear flow-volume curves, and evidence of air trapping. Furthermore, the flight attendants had significantly decreased diffusing capacity (77.5±11.2 %predicted normal) with 51% having a diffusing capacity below their 95% normal prediction limit.
Conclusions: This cohort of healthy never-smoking flight attendants who were exposed to SHS in the aircraft cabin showed pulmonary function abnormalities suggestive of airway obstruction and impaired diffusion.